The endoplasmic reticulum aminopeptidase ERAP1 regulates innate and adaptive immune responses by trimming peptides for presentation by major histocompatibility complex (MHC) class I molecules.Previously, we have shown that genetic or pharmacological inhibition of ERAP1 on murine and human tumor cell lines perturbs the engagement of NK cell inhibito
This paper looks for an interpretation of the phonetic factors causing consonant lenition and elision to occur through an analysis of intervocalic [j] in Majorcan, a dialect of Catalan spoken in the Mediterranean island of Majorca.Articulatory and acoustic data for several Majorcan Catalan speakers still producing the palatal glide in all word posi
Problem: Emerging bacterial antimicrobial (antibiotic) resistance (AMR) is a global threat to human health.However, a majority of lower income countries do not have microbiological diagnostic testing for prompt, reliable confirmation of bloodstream infection and identification of AMR.Context: Clinicians in Pacific island nations are increasingly ch
The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients.Deletion of exon 52 impedes expression of several brain dystrophins (Dp427, Dp260 and Dp140), thus providing a key model for studying the cognitive impairment associa
The purpose of this work was to study bias error in acceleration-based transfer alignment, which is probably caused by cross-correlation between the dynamic lever-arm and the linear motion of a ship.A new prediction model for the cross-correlation-caused error is proposed in this paper.We adopt the Bernoulli-Euler Beam as a simplified ship hull-gir